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As cyanosis (of griech. "„blue "“) one designates a violet to bluish discoloration of the skin (usually in the face), the mucous membranes, the lips and the fingernails with humans. The special hue does not have to arise with it within all ranges mentioned at the same time or equally strongly.

Causes

The cause of a cyanosis is usually a Unterversorgung of the blood with oxygen, is it by to small photograph possibility (for example to small concentration at oxygen in the environment) or by to long Diffusionsstrecken when diseased changes the lung. The bluish colouring results from the oxygen-dependent colouring of hemoglobin. During oxygen-rich (oxygeniertes) hemoglobin is light red colored, appears oxygen-poor (desoxygeniertes) hemoglobin dark red/blue. A cyanosis becomes usually visible starting from approximately 5 g/dl desoxygeniertem hemoglobin (HB).

Cyanotic conditions can be also symptoms of a heart error or result from secondary and/or subsequent illnesses of a heart error.

Cyanosis forms

Differences generally becomes between peripheral cyanosis (exhaustion cyanosis) and central cyanosis (mixture cyanosis), whereby both forms can be present also at the same time:

  • peripheral cyanosis by increased oxygen exhaustion in the periphery of the body due to slowed down blood river comes it to peripheral cyanosis. She is to be seen primarily at the discoloration of peripheral body sections as for example to the skin and the extremities. It can be causally justified in a reduction of the kardialen cardiac output (heart insufficiency, by a Venenthrombose, Varikosis, neutrally caused Akrozyanose or blood changes (Polyglobulie, Kryoglobulian¤mie).
  • central ZyanoseEine central cyanosis develops due to a decreased oxygen saturation of the blood in the lung and shows up in a discoloration in particular the mouth mucous membranes, the tongue, the lips and the binding skin (Konjunktiven) and in further body regions. It is causally justified either pulmonal (insufficient oxygen saturation of the blood in the lung) or kardial (mixture of oxygen-rich and oxygen-poor blood in the heart due to a heart error with shunting formation).
Differences to become to be able peripheral and central cyanosis by control of the tongue color: with peripheral cyanosis the tongue does not discolour usually bluish, with central cyanosis is the cyanotic discoloration however to be recognized.
  • occurrence of a cyanosis as consequence of a shunting reversal with heart errors, which were at first not connected with a cyanosis, is called late cyanosis or iron mixing he reaction.

as a cause of a cyanosis

A special and comparatively rare disturbance, which releases a cyanosis, is the so-called It results from a increased concentration of (Met HB, oxidized form of hemoglobin) in the red blood corpuscles. This can be justified in a hereditary enzyme defect (not treatable) or to be caused by the income of substances, which affect oxidizing the red blood coloring material like cyanide potash, chlorates, aromatic amines, increased nitrate concentration in food or drinking water of over 100 mg/l. Met HB cannot transport and by the reaction loses the iron its ability to deposit oxygen bound in hemoglobin and deliver at organs and parts of the body. If the concentration of Met HB rises around more as 10% (more than 70-80% are deadly) in entire hemoglobin due to its, it comes to oxygen deficiency in the blood and a cyanosis develops. During a blood investigation the slate-grey color of the blood is noticeable. Symptoms of the oxygen deficiency in the blood are frequently swindle, nausea, headache, acceleration of the heart frequency, difficulty in breathing and behaviourness (Somnolenz). Sometimes in particular for babies and infants a is dangerous and their effects in these age groups with the symptoms of a heart error is confounded. Thus valuable time can be lost with the therapy. For treatment first the respectively damaging substance must be avoided.

See also: Pulmonary edema

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