Jonas Edward Salk (* 28. October 1914 in New York town center, "† 23. June 1995 in La Jolla (California)) were an US-American physician and Immunologe. It developed the dead inoculation against child paralysis (Polio).

Salk was born on 28 October 1914 in New York town center. There it visited also the college and studied afterwards medicine to the New York University. it was attained a doctorate to 1939 to the doctor of the medicine (Medical Doctor).

Its first activity as a physician took up Salk at the Mount Sinai hospital to New York. Later it researched at the University OF Michigan over flu vaccines. 1947 one appointed it as the director of a virus research institute at the University of Pittsburgh. There it developed an effective vaccine against the child paralysis (Poliomyelitis), caused by viruses, which he first actually and its family tested as the first. It concerned a dead vaccine, with which the Polioviren with Formalin was killed. An infection of the persons who can be inoculated and a possible spreading of the illness could be excluded by killing the viruses.

In thereupon Salk that it is not only producible from weakened - thus still "“living"” viruses could prove starting and US-American inoculation study up to then largest with more than one million participants - functional Vakzinen. The most important publication of the results of this work appeared in the year 1955, in this year took place also the permission of the vaccine in the USA. Within short the spreading could be back-pushed by Polio in the USA on a fifth and today is almost exterminated the illness in the industrial nations. Last success is to be due however also to the sip inoculation developed by Albert Sabin, which exhibits the large advantage that it is orally used and as with Salks vaccine does not have to be squirted. However it acts with that, due to the more pleasant administration and at the same time more effective protection more popular sip inoculation, around a living person vaccine with weakened viruses, which saves also some risks.

Despite the large success of his vaccine many colleagues dissociated themselves from Salk, since it ignored unwritten laws of the "“Scientific Community"”. Thus it omitted it appreciating crucial pre-working from coworkers and colleagues to; to call here among other things the micro biologists and epidemiologist John F would be. Enders, Thomas's H. Weller and Frederick C. crawl in. On the other hand stepped Salk with vain to the American public. He was celebrated by this however like a hero: many roads, bridges and schools as well as the new inoculation were designated after him.

Salk decided later to create its own scientific Institut. This was opened 1967 in La Jolla, to a suburb of San Diego (California). Today the Salk of institutes is a biomedical research center renowned internationally.

In the last years of its life Salk strove around the development of a HIV vaccine. Salk died on 23 June 1995 in La Jolla (California).

Salks of inoculation attempts against HIV/Remune

1987 created Salk the Pharmaunternehmen IRC (immune Response corporation) for the study of an experimental vaccine that the immune answer with HIV infection to strengthen should. The vaccine became immunogen as HIV-1, "“Salk vaccine"” and as AG1661 admits. The planned trade name was Remune its name in the public became public likewise. After its death those was taken over IRC von Pfizer, the development was stopped 1999 because of missing effectiveness. In Thailand however still further studies run to Remune.

Related links

• Salk Institue for Biological Studies
• Biography with the Academy OF Achievement
• Patent US patent 5,256,767: Inoculation against HIV

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